Content
1. Molecular diseases ……………………………………………………………………………………….. 2
2. Post-translational regulation of proteins ………………………………………………………… 6
3. Intercellular interactions and signal transduction …………………………………………… 12
4. Types of plasma membrane receptors ……………………………………………………………. 14
5. Participation of secondary mediators in signal transduction ……………………………. 25
6. Hormones ………………………………………………………………………………………………….. 35
6.1 Pituitary hormones ……………………………………………………………………………………. 37
6.1.1 Hormones from the anterior pituitary gland ……………………………………………… 38
6.1.2 Neurohypophysis Hormones (Posterior Pituitary) …………………………………….. 52
7. Hormones regulating water-salt metabolism …………………………………………………. 55
8. Pancreatic hormones ………………………………………………………………………………….. 59
9. Catecholamines ………………………………………………………………………………………….. 64
10. Gastrointestinal hormones …………………………………………………………………………. 66
11. Hormones with intracellular receptors ………………………………………………………… 68
12. Apoptosis …………………………………………………………………………………………………. 78
13. Mechanisms of oncogenesis ……………………………………………………………………….. 85
14. Pathobiochemical mechanisms of diabetes mellitus ……………………………………… 94
15. Biochemistry of blood …………………………………………………………………………………104
16. Mechanisms of cell adhesion ……………………………………………………………………… 131
17. Extracellular matrix (ECM) ………………………………………………………………………… 142
18. Bones as mineralized connective tissue ……………………………………………………….. 150
18.1 Biochemistry of cartilage ………………………………………………………………………….. 155
18.2 Calcium metabolism ………………………………………………………………………………… 157
18.3 Hormones affecting calcium metabolism …………………………………………………… 158
18.4 Biochemistry of teeth ………………………………………………………………………………. 160
19. Biochemistry of nutrition ……………………………………………………………………………164
20. Biochemistry of the liver. Metabolic functions. Synthesis of specific products. Biotransformation of xenobiotics …………………………………………………………………………. 184
Bibliography ………………………………………………………………………………………………….. 191