for first year students in Medicine and Dental Medicine

The Lecture Guide covers the basic topics included in the teaching program in Medical Biology. A synopsis of lectures on molecular, cell and developmental biology and fundamental immunology is presented. The aim of the authors is to help students get the rationale and discover the basics and the links between all the modules covered by the lecture course. Using this guide students could follow easier the lecturer and catch more details from the presentations. It is not a textbook but just an additional training aid to the basic references recommended by the lecturer.

1.NUCLEIC ACIDS - V. Sarafian – 5
2.REPLICATION OF DNA. REPARATIVE SYNTHESIS - V. Sarafian – 14
3.TRANSCRIPTION. REGULATION OF GENE ACTIVITY - V. Sarafian – 22
4.TRANSLATION. GENETIC CODE - V. Sarafian – 31
5.GENE STRUCTURE AND FUNCTIONS -  V. Sarafian – 41
6.SUBMICROSCOPIC AND MICROSCOPIC STRUCTURE OF CHROMOSOMES. NORMAL KARYOTYPE - Y. Feodorova – 47
7.MUTATIONS. PATHOLOGIC KARYOTYPE - V. Sarafian – 62
8.GENETIC DISEASES - V. Sarafian – 69
9.EPIGENETICS - V. Sarafian – 87
10.GENETIC ENGINEERING. GENE THERAPY - V. Sarafian – 84
11.MOLECULAR ENGINEERING - M. Kazakova – 91
12.CELL REPRODUCTION. REGULATION OF THE CELL CY¬CLE - M. Kazakova – 93
13.MEIOSIS. GAMETOGENESIS - M. Kazakova – 104
14.FERTILIZATION. EMBRYONIC DEVELOPMENT - M. Kazakova – 115
15.APOPTOSIS - V. Sarafian – 123
16.TUMOR BIOLOGY - V. Sarafian – 131
17.INNATE AND ADAPTIVE IMMUNITY - V. Sarafian – 138
18.ANTIGENS. CHARACTERISTICS - V. Sarafian – 146
19.IMMUNE SYSTEM. LYMPHOID ORGANS - V. Sarafian – 150
20.LYMPHOID CELLS. ANTIGEN ELIMINATION - V. Sarafian – 155
21.TYPES OF IMMUNE RESPONSE. ANTIBODIES. IMMUNOGLOBULIN CLASSES - V. Sarafian – 165
22.BLOOD GROUP ANTIGENS.  ABO/H/ AND RHESUS SYSTEMS - V. Sarafian – 171
23.MHC. ANTIGEN PROCESSING AND PRESENTATION - V. Sarafian – 177
24.CELLULAR INTERACTIONS. CYTOKINES - V. Sarafian – 181
25.KINETICS AND GENETICS OF IMMUNE RESPONSE.  COMPLEMENT SYSTEM  - V. Sarafian – 186
26.IMMUNOLOGICAL TOLERANCE - V. Sarafian – 196
27.IMMUNITY IN TRANSPLANTATIONS AND PREGNANCY - V. Sarafian – 200
28.TUMOR IMMUNOLOGY - V. Sarafian – 206
29.REACTIONS OF HYPERSENSITIVITY - V. Sarafian – 211
30.IMMUNOBIOLOGY OF HIV. AIDS - V. Sarafian – 218